Subcutaneous HCT116 Xenograft model in PBMC-humanized mouse
Cell information:
HCT116 cells are human colon cancer cells that express CEA, PD-L1 and other proteins, and carry the Kras G13D mutation. Click for more information (https://depmap.org/portal/cell_line/ACH-000971?tab=mutation).
Model information:
For subcutaneous inoculation, the mouse strains are NOG and NOG-dko, and matrigel is required for tumor formation. 3.6*106 PBMC cells per mouse were injected into the tail vein on the day of inoculation.


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