Subcutaneous A375 Xenograft model in PBMC-humanized mouse
Cell information:
A375 cells are derived from human malignant melanoma cells, which express PD-L1, PD-L2, OX40L and other immune checkpoint proteins.
Model information:
For subcutaneous inoculation, the mouse strains are NOG and NOG-dko, and matrigel is required for tumor formation. On the day of inoculation, 2.0*106 PBMC cells per mouse were injected into the tail vein.


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