Blood-brain Barrier Permeability Study

Drugs that target the central nervous system need to be able to effectively penetrate the blood-brain barrier, and blood-brain barrier permeability evaluation experiments can help understand the distribution ratio of compounds in plasma and brain tissue.

Blood-brain Barrier Permeability Study Protocol

Species Mouse, rat,
Dosing route P.O., I.V., I.M.; I. P. etc
Groups multiple groups, one group per time point
Dosage TBD
Dosing frequency Single dose
Number of animals 3 per group
Time points TBD
Analysis method LC-MS/MS
Data analysis Winnonlin
Integrate Drug Discovery Service
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