In the early history of drug development, Drug Metabolism and Pharmacokinetics (DMPK) was mainly used to evaluate the safety of drugs in the drug development process, but today, DMPK has become crucial research area in the drug discovery and development process. About 20 years ago, the defect of the candidate drug's DMPK was considered a factor in the failure of early clinical trials. With the evolution of technology, preclinical DMPK research can help select the best drug candidates to enter the clinical stage and increase the success rate of clinical trials.

In the process of drug development, DMPK is mainly to help optimize the characteristics of the compound in terms of absorption, distribution, metabolism, excretion and possible DDI. Due to the iterative optimization, the DMPK experiment should not only be as fast as possible, but also as cost-effective as possible. DMPK experiments mainly involve two aspects, in vitro ADME and PK experiments in animals.

At TruwayBio, we have developed, optimized and validated in vitro ADME experiments, which can be used for routine compound screening. At the same time, we can also carry out in vivo PK experiments on a variety of animal species.

Cooperate with TruwayBio, a safe choice. If you are not satisfied with the data quality of DMPK studies, we guarantee 100% free.

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